ESUN

A Periodical for the Sarcoma Community

June 2011 - Volume 8, Number 3

So Many Terms, So Much to Learn …

Editorial by Bruce Shriver, PhD

Dermatofibrosarcoma Protuberans (DFSP): An Update on Molecularly Targeted Therapy of Advanced Cases

Drs. Rutkowski and Switaj discuss why Imatinib is currently the gold standard therapy of inoperable, metastatic, or recurrent cases of DFSP.

Targeting Bone Microenvironment as a New Therapeutic Strategy in Ewing’s Sarcoma: Combination of Zoledronic Acid with Chemotherapy in Mouse Preclinical Models

In this experimental plan, Drs. Odri, Corradini, and Rédini describe their studies, the impact of which may be to propose zoledronic acid as adjuvant therapy in Ewing sarcoma patients for the next European protocol.

Somatic Mutation Profiling of PI3K Pathway in Uterine Carcinosarcoma/ Malignant Mixed Mullerian Tumors

In this experimental plan, Drs. Clarke, Hale, Gilks, and Boutros describe a study in which they will analyze the mutation profile of the genes involved in the PI3K pathway in an annotated cohort of uterine carcinosarcomas.

Announcements

$90,000 Grant Awarded for Ewing's sarcoma Research

The Liddy Shriver Sarcoma Initiative has awarded a $90,000 grant for Ewing's sarcoma research at the University of Nantes in France.

$50,000 Grant Awarded for Carcinosarcoma (MMMT) Research

The Liddy Shriver Sarcoma Initiative has awarded $50,000 for an international collaborative study on carcinosarcomas.

Translated Articles

尤文氏肉瘤家族性肿瘤

Dr. Tian and Dr. Yang provide a Chinese translation of the ESUN review article about the Ewing's Sarcoma Family of Tumors.

Les Sarcomes d’Ewing

Dr. Dutour provides a French translation of the ESUN review article about the Ewing's Sarcoma Family of Tumors.

Los tumores de la familia del sarcoma de Ewing (TFSE)

Dr. Tejerina provides a Spanish translation of the ESUN review article about the Ewing's Sarcoma Family of Tumors.