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ESUN Index

August 2008

The Electronic Sarcoma Update Newsletter, Vol. 5, No. 4

Each of the words or phrases that are underlined and in a bold blue type in ESUN are hyperlinks to websites, documents or articles. Each title in the table of contents, In This Issue, is a link to the specific article. All the external hyperlinks appearing in ESUN were valid when the issue of ESUN was published. If you find any broken links, please send us a note about them. The document hyperlinks typically open PDF documents, so you should have the Adobe Acrobat Reader installed on your system in order to read them. 

 

In This Issue

Feature Articles

Some Important Milestones: Over $1 Million Dollars Raised and 21 Research Studies Funded

Editorial by Bruce Shriver, PhD 

CTOS Op Ed: PET and Sarcoma 

Janet Eary, MD and Ernest Conrad, MD contend that time has come for PET imaging to be accepted by the sarcoma community as an important contributor of patient specific information for treatment planning and assessment.

High throughput miRNA expression profiling for well differentiated and de-differentiated liposarcoma

Dina Lev, MD and Matt van de Rijn, MD, PhD describe their research to identify unique microRNA expression profiles of well differentiated and de-differentiated liposarcoma.

PEDF: a potential therapeutic agent for osteosarcoma

Peter Choong, MD and Crispin Dass, PhD describe their research into PEDF which combines basic science investigations with a prominent translational element.

EWS/FLI and its targets in Ewing’s sarcoma: a progress report and future directions

Stephen Lessnick, MD, PhD. describes research that is focused on understanding the function of NR0B1 in Ewing’s sarcoma.

A mouse model of chordoma

Brain Harfe, PhD describes his research into the development of a mouse model for chordoma which has the potential to speed up the development of new therapies for chordoma.

The International Sarcoma Awareness Week

Bruce Shriver and Mary Sorens summarize the 2008 iSAW and describe infrastructure enhancements for the 2009 Team Sarcoma Initiative events.

A Brief Update on SARC

Denise Reinke, MS, NP, President and Chief Operations Officer of SARC

An Update on the SFA Patient Registry

Matthew Alsante, Executive Director, Sarcoma Foundation of America  

A Partial Index to Articles that have Appeared in ESUN

We give an updated partial index to ESUN articles.

Regular Columns

Clinical Trial News 

Tom Swartz describes various clinical trials
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Currently Accepting Eligible Patients (not previously published in ESUN)

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Not Yet Recruiting Patients (not previously published in ESUN)

Odds & Ends

Pointers to resources and abstracts of interesting articles. In this issue: 
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Quality-of-Life Assessment for Routine Oncology Clinical Practice

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PET for Sarcomas Other Than Gastrointestinal Stromal Tumors

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Project FLAG

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Cancer Survivor Research Conference Presentations Available

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Brostallicin as First Line Therapy for Advanced or Metastatic Soft Tissue Sarcoma

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The National Cancer Institute's Understanding Cancer Series of Tutorials

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Epigenetics at the Epicenter of Modern Medicine

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BioAlive

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CELLS Alive

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European Bioinformatics Institute

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Pediatric Non-rhabdomyosarcoma Soft Tissue Sarcomas

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Study Reveals Inconsistencies in Access to Drugs for Rare Cancers in England

Research Corner

Abstracts of recent sarcoma-related research articles. In this issue: 
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Modes of resistance to anti-angiogenic therapy

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EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy

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Diagnostic and prognostic gene expression signatures in 177 soft tissue sarcomas: hypoxia-induced transcription profile signifies metastatic potential

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Clinical Significance of CXC Chemokine Receptor-4 and c-Met in Childhood Rhabdomyosarcoma

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Intraarterial Chemotherapy for Extremity Osteosarcoma and MFH in Adults

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Fluorescence in situ hybridization is a useful ancillary diagnostic tool for extraskeletal myxoid chondrosarcoma

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Synovial sarcoma of children and adolescents: The prognostic role of axial sites

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DAX1, a direct target of EWS/FLI1 oncoprotein, is a principal regulator of cell-cycle progression in Ewing's tumor cells

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A Pilot Study of Consolidative Immunotherapy in Patients with High-Risk Pediatric Sarcomas

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Midkine Enhances Soft-Tissue Sarcoma Growth: A Possible Novel Therapeutic Target

Stories of Courage and Hope

Tom Swartz abstracts several inspiring stories we have recently encountered about patients or caregivers that tell of the strength that some are blessed with in dealing with sarcoma. In this issue: 
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Cancer survivors turn experiences into theatrical performances

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Three-year-old survives sarcoma

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Remembering Lindsey Sowles

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Tyler Copley dies after long bout with cancer

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Tributes to young man who died from alveolar rhabdomyosarcoma

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"Reid’s Ride" raises $75,000

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"Soccer 'Round the Clock"

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Team Kevin Fitz takes up Challenge

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Teenager Wins Battle Her Father Lost

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Pastor Uses Faith To Battle Sarcoma

Our Initiatives

Brief descriptions of some of the Liddy Shriver Sarcoma Initiative projects are presented. In this issue:

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Bridge Tournament in the Netherlands Raises $58,000 for Ewing's Sarcoma Research

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Participants in the Dublin Mini Marathon Raise over $18,000 for Osteosarcoma Research

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2009 Team Sarcoma Event Planning Underway

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The Faces of Sarcoma Project

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The "Sarcoma Knows No Borders" Bracelet 

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Team Sarcoma T-Shirts and other Odds & Ends

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Music CD, The Circle, Benefits Sarcoma Research

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Clinical trial abstracts now exceed 300

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Guest Book

General Information

Disclaimer

Medical Editorial Board and Editorial Staff

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Topics and Feedback

Please send us your recommendations for topics that you would like to see covered in ESUN as well as any other comments or feedback that can be useful to us. We also welcome contributions of essays and articles that are relevant to ESUN and its intended audience

 

V5N4 ESUN Copyright © 2008 Liddy Shriver Sarcoma Initiative.

 

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