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April 2007

The Electronic Sarcoma Update Newsletter, Vol. 4, No. 2

Each of the words or phrases that are underlined and in a bold blue type in ESUN are hyperlinks to websites, documents or articles. Each title in the table of contents, In This Issue, is a link to the specific article. All the external hyperlinks appearing in ESUN were valid when the issue of ESUN was published. If you find any broken links, please send us a note about them. The document hyperlinks typically open PDF documents, so you should have the Adobe Acrobat Reader installed on your system in order to read them.

 

In This Issue

Feature Articles

An International Sarcoma Awareness Week

Editorial by Bruce Shriver

CTOS OP ED  

Dr. Lor Randall follows-up on Dr. Ian Judson's OP Ed piece in the last issue of ESUN. 

CTOS OP ED: Questions, Comments and Counterpoints 

Dr. Judson responds to a reader's comment.

Leiomyosarcoma of Bone and Soft Tissue: A Review

Drs. Weaver and Abraham explore bone and soft tissue leiomyosarcomas in this review article.

Leiomyosarcoma of the Uterus: A Review

Drs. Ghosh, Hecht, Ferzandi and Awtrey focus on uterine leiomyosarcoma in this review article.

Cytarabine for the Treatment of Ewing's Sarcoma

Drs. DuBois, Grier, and Stegmaier discuss laboratory research that suggests cytarabine may be useful for patients with Ewing's sarcoma.

Chordoma Research Study Funded

A research project being undertaken by Dr. Silvana Pilotti in the Laboratory of Experimental Molecular Pathology of the Department of Pathology at the Fondazione IRCCS Istituto dei Tumori in Milan, Italy is announced.

Two Distinguished Physicians Join ESUN's Medical Editorial Advisory Board

We are pleased to announce the Dr. Junya Toguchida, M.D., Ph. D and Richard Gorlick, M.D., have joined our Medical Editorial Advisory Board.

From a Nurse's Perspective

Denise Reinke discuss SARC and her next article.

Sarcoma Calendar

A listing of upcoming conferences, meetings, workshops, seminars, events and fundraisers.

Regular Columns

Clinical Trial News 

Tom Swartz describes various clinical trials
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Currently Accepting Eligible Patients (not previously published in ESUN)

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Not Yet Recruiting Patients (not previously published in ESUN)

Odds & Ends

Pointers to resources and abstracts of interesting articles. In this issue's column:
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HopeLab 

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Virtual-Reality Therapy

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Cancer Research UK Secures Fenretinide Orphan Drug License

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More Gene Mutations Drive Cancer Than Previously Thought

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Cancer Pain: Your Guide to Relief™

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Simple Two-Gene Test Sorts Out Similar Gastrointestinal Cancers

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NCCN Clinical Practice Guidelines — Soft Tissue Sarcoma 2007

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Grind For Life

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SOS Desmoïde

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How Many List Members Does It Take to Change a Light Bulb?

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Sarcoma Videos on YouTube

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Radiation-Induced Fractures a Significant Challenge After Sarcoma Surgery

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ARIAD Provides Update Regarding AP23573 Phase 3 Trial in Metastatic Sarcoma

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Monies Will Be Used to Investigate the Neural Crest Origin of Ewing's Sarcoma

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Oncolytics Biotech Inc. Proceeds to Initiate U.S. Phase II Sarcoma Clinical Trial for Sarcoma Patients with Lung Metastasis

Research Corner  

Abstracts of recent sarcoma-related research articles. In this issue:
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Diagnosis and Surgical Therapy of Uterine Sarcoma – A Retrospective Study

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Leiomyosarcoma Metastases to the Spine. Case Series and Review of the Literature

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Progress Against Synovial Sarcoma

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The Biology of Metastasis to a Sanctuary Site

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Childhood Cancer Survivors At Increased Risk Of Sarcoma

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Outcomes of Older Patients with Localized Ewing’s Sarcoma Similar to Younger Patients

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Benefit of Surgical Treatment of Lung Metastasis in Soft Tissue Sarcoma

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Phase I Evaluation of a Fully Human Anti–{alpha}v Integrin Monoclonal Antibody (CNTO 95) in Patients with Advanced Solid Tumors

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Isolated Limb Perfusion with Tumor Necrosis Factor Alpha and Melphalan for Locally Advanced Soft Tissue Sarcoma: Three Time Periods at Risk for Amputation

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Dasatinib Inhibits Migration and Invasion in Diverse Human Sarcoma Cell Lines and Induces Apoptosis in Bone Sarcoma Cells Dependent on Src Kinase for Survival

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Phase I Pharmacokinetic and Pharmacodynamic Study of 17-N-Allylamino-17-Demethoxygeldanamycin in Pediatric Patients with Recurrent or Refractory Solid Tumors: A Pediatric Oncology Experimental Therapeutics Investigators Consortium Study

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Prospective Multicentric Randomized Phase III Study of Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors Comparing Interruption Versus Continuation of Treatment Beyond 1 Year: The French Sarcoma Group

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Phase I Study of Inhaled Doxorubicin for Patients with Metastatic Tumors to the Lungs

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High-dose chemotherapy and autologous peripheral blood stem cell transfusion for adult and adolescent patients with small round cell sarcomas

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Therapeutic Advances in the Treatment of Brain Metastases

Stories of Courage and Hope 

Tom Swartz abstracts several inspiring stories we have recently encountered about patients or caregivers that tell of the strength that some are blessed with in dealing with sarcoma. In this issue's column:
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Surviving the Odds One Day at a Time

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Survivor's Battle With Cancer Is Over, but She Continues the Fight

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Party and Celebrate Life

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High School Grad Leaves an Inspiring Legacy

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Wrapped in Comfort and Healing With Homemade Shawls

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Blairsville Teen Inspires Family, Iraq Soldier Even After Death

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Boy’s Love of Golf and Life Drives Outreach

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Survivor

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"Music Man" Wins Top Teaching Award

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Miracle Champion Child on a Mission

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Author Survives Disease to Summit Everest

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Teen Living with Cancer Reveals Bravery, Beauty

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Son’s Cancer Inspires Mother To Help Other Families

Our Initiatives

Brief descriptions of some of the Liddy Shriver Sarcoma Initiative projects are presented. In this issue:

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Team Sarcoma 2007 Initiative

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The "Sarcoma Knows No Borders" Bracelet 

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Music CD, The Circle, Benefits Sarcoma Research

General Information

Disclaimer

Medical Editorial Board and Editorial Staff

Registering to Receive Notifications About ESUN

Send us a note containing your e-mail address if you would like to receive a note when the next issue of ESUN is published.

Topics and Feedback

Please send us your recommendations for topics that you would like to see covered in ESUN as well as any other comments or feedback that can be useful to us.  We also welcome contributions of essays and articles that are relevant to ESUN and its intended audience

 

V4N2 ESUN Copyright © 2007 Liddy Shriver Sarcoma Initiative.

 

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